ADENOSINE A2B RECEPTOR AGONISTS

摘要

The present invention provides compounds of the formula wherein R¹, R², R³ and n have meaning as described in the specification, as adenosine A_2B receptor agonists and, thus, may be employed for the treatment of diseases in mammals that are mediated by the A_2B receptor including, but not limited to, septic shock, cystic fibrosis, impotence, diarrhea, and cardiac diseases Cardiac diseases include hyperplasia consequent to hypertension, arteriosclerosis, and heart attack