RhoA mediated signaling pathways are manipulated with specific domains of the RhoA protein that are translocation modified by conjugation or fusion to a transport domain. The compounds find use in therapeutic and research methods where it is desirable to selectively inhibit RhoA.
申请公布号
WO2005072141(A3)
申请公布日期
2007.12.06
申请号
WO2005US01251
申请日期
2005.01.14
申请人
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;LAUDANNA, CARLO;BUTCHER, EUGENE, C.