发明名称 |
PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE PIPERIDINE COMPOUND |
摘要 |
<p>A process for production of a piperidine compound having a syn-configuration represented by the general formula [I] or a salt thereof, comprising reducing a compound represented by the general formula [II]. [I] wherein the solid bold line represents such a bond that each of the substituents at position-2 and position-4 in the piperidine ring can have a syn-configuration; and other variable symbols are as defined above. [II] wherein the ring A represents a benzene ring which may have a substituent; R<SUP>2</SUP> represents a hydrogen atom, a hydroxyl group which may have a substituent, an amino group which may have a substituent, an alkyl groupwhich may have a substituent, a carbonyl group which has a substituent, or a halogen atom; and M represents an alkali metal or a hydrogen atom.</p> |
申请公布号 |
WO2007139211(A1) |
申请公布日期 |
2007.12.06 |
申请号 |
WO2007JP61155 |
申请日期 |
2007.06.01 |
申请人 |
MITSUBISHI TANABE PHARMA CORPORATION;MATSUMAE, HIROAKI;MORI, YOSHIKAZU;MATSUYAMA, KOJI;MORIYAMA, NORIAKI |
发明人 |
MATSUMAE, HIROAKI;MORI, YOSHIKAZU;MATSUYAMA, KOJI;MORIYAMA, NORIAKI |
分类号 |
C07D211/46;A61K31/451;A61K31/453;A61K31/454;A61K31/4545;A61K31/5377;A61K31/541;A61P1/00;A61P1/08;A61P9/00;A61P13/02;A61P25/00;A61P25/04;A61P25/24;A61P29/00;A61P37/08;C07D211/58;C07D211/62;C07D401/12;C07D405/12 |
主分类号 |
C07D211/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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