PEPTIDE SUBSTANCE STIMULATING LIVER TISSUE REGENERATION, PHARMACEUTICAL COMPOSITION ON ITS BASE AND THE METHOD OF ITS APPLICATION

摘要

The invention is related to the medicinal means of treatment of liver diseases and can be used as a means of stimulating liver tissue regeneration. There is proposed a peptide glutamyl-aspartyl-leucine of the general formula H-Glu- Asp-Leu-OH sequence 1 [SEQ ID NO:1] capable of stimulating liver tissue regeneration. There is proposed a pharmaceutical composition stimulating liver tissue regeneration, containing peptide glutamyl-aspartyl-leucine of the general formula H-Glu- Asp-Leu-OH sequence 1 [SEQ ID NO:1] as its active base, as well as a pharmaceutically acceptable carrier. There is proposed a method of stimulation the regeneration of liver tissue consisting in the administration to a patient of the pharmaceutical composition, containing peptide glutamyl-aspartyl-leucine of the general formula H-Glu-Asp- Leu-OH sequence 1 [SEQ ID NO:1] as its active base, in the dose of 0,01 - 100 µg/kg of body weight at least once a day during a period necessary for attaining the therapeutic effect, such administration being performed parenterally.