发明名称 FUSED HETEROBICYCLIC KINASE INHIBITORS
摘要 Compounds of the formula (I) and pharmaceutically acceptable salts thereof, wherein X<SUB>1</SUB>, X<SUB>2</SUB>, X<SUB>3</SUB>, X<SUB>4</SUB>, X<SUB>5</SUB>, X<SUB>6</SUB>, X<SUB>7</SUB>, R<SUP>1</SUP>, and Q<SUP>1</SUP> are defined herein, inhibit kinase enzymes and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer. The compounds are also useful in the treatment of inflammation, allergy, asthma, disease and conditions of the immune system, disease and conditions of the nervous system, cardiovascular diseases, disease and conditions of the eye, dermatological diseases, osteoporosis, diabetes, multiple sclerosis, and infections.
申请公布号 WO2007084667(A3) 申请公布日期 2007.12.06
申请号 WO2007US01439 申请日期 2007.01.18
申请人 OSI PHARMACEUTICAL, INC.;ARNOLD, LEE, D.;CHEN, XIN;DONG, HANPING;GARTON, ANDREW;MULVIHILL, MARK, JOSEPH;SMITH, COLIN PETER, SAMBROOK;THOMAS, GERARD, HUGH;KRULLE, THOMAS, MARTIN;WANG, JING 发明人 ARNOLD, LEE, D.;CHEN, XIN;DONG, HANPING;GARTON, ANDREW;MULVIHILL, MARK, JOSEPH;SMITH, COLIN PETER, SAMBROOK;THOMAS, GERARD, HUGH;KRULLE, THOMAS, MARTIN;WANG, JING
分类号 C07D471/04;A61K31/437;A61P35/00 主分类号 C07D471/04
代理机构 代理人
主权项
地址