| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method and a system for improving a mathematical model of organism metabolism at a current technical level. <P>SOLUTION: This application provides a method and a system for in-silico or bioinformatic modeling of organic cellular metabolism. The method and the system include processes of: constructing a flux balance analysis model; and applying various constraints to the flux balance analysis model. The constraints includes: qualitative kinetic information constraints, qualitative regulatory information constraints, and differential DNA microarray experimental data constraints. In addition, the application provides for computational procedures for solving metabolic problems. <P>COPYRIGHT: (C)2008,JPO&INPIT |
