发明名称 |
SINOMENINE DERIVATIVES AND PREPARATION AND USES THEREOF |
摘要 |
The present invention relates to the preparation and pharmacological use of sinomenine derivatives of formula I . The approach disclosed herein is the modification of D ring by- substituting for R. Additional substitutions in the other rings are also provided herein. Several of the sinomenine derivatives have significantly greater anti-inflammation activity when compared with the parent compound.
|
申请公布号 |
WO2007070703(A3) |
申请公布日期 |
2007.12.06 |
申请号 |
WO2006US48086 |
申请日期 |
2006.12.15 |
申请人 |
NATUREMED GROUP CORPORATION;WANG, JIE;PAN, YI |
发明人 |
WANG, JIE;PAN, YI |
分类号 |
A61K31/485;C07D221/28 |
主分类号 |
A61K31/485 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|