发明名称 PROCESS FOR THE PURIFICATION OF SUBSTITUTED BENZOXAZOLE COMPOUNDS.
摘要 <p>The present invention provides processes for the purification of substituted benzoxazole compounds of formla (I), and in particular 2-(3-fluoro-4-hydroxy-phenyl)-7-vinyl- benzooxazol-5-ol. The processes include recrystallizing the compound from a solution comprising acetone and acetonitrile; treating the crude purified product with a clarifying agent in a solution comprising ethyl acetate, and precipitating or triturating the compound from a mixed solvent system.</p>
申请公布号 MX2007010895(A) 申请公布日期 2007.12.05
申请号 MX20070010895 申请日期 2006.03.06
申请人 WYETH. 发明人 IERA, SILVIO
分类号 C07D263/56 主分类号 C07D263/56
代理机构 代理人
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