发明名称 |
IMMUNOGENIC COMPOSITION COMPRISING AN ANTIGEN AND A LIPOPROTEIN |
摘要 |
<p>Immunological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself be antigenic or immunogenic. The antigen can be influenza HA and the lipoprotein a recombinantly expressed product having an OspA leader for lipidation and PspA for the protein portion. The antigen can be OspC and the lipoprotein OspA. The components of the composition are co-administered. A potentiated immunological response is obtained by the compositions and methods.</p> |
申请公布号 |
IL118579(A) |
申请公布日期 |
2007.12.03 |
申请号 |
IL19960118579 |
申请日期 |
1996.06.05 |
申请人 |
CONNAUGHT LABORATORIES, INC.;ROBERT S. BECKER;ROBERT C. HUEBNER;MARYANN GRAY;KAREN S. BISCARDI;LORNE F. ERDILE;BRUNO GUY |
发明人 |
ROBERT S. BECKER;ROBERT C. HUEBNER;MARYANN GRAY;KAREN S. BISCARDI;LORNE F. ERDILE;BRUNO GUY |
分类号 |
C12N15/09;A61K31/00;A61K38/00;A61K39/00;A61K39/02;A61K39/09;A61K39/102;A61K39/116;A61K39/145;A61K39/295;A61K39/385;A61K39/39;A61P31/00;A61P31/04;A61P31/12;A61P31/16;C07K14/195;C07K14/20;C07K14/285;C07K14/315;C12P21/08;C12R1/19 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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