| 发明名称 |
Hydroxyethylamine derivatives for the treatment of alzheimer's disease |
| 摘要 |
Hydroxyethylamine compounds of formula (I) as defined in the description having Asp2 (-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated - amyloid levels or -amyloid deposits, particularly Alzheimer's disease.
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| 申请公布号 |
NZ539841(A) |
申请公布日期 |
2007.11.30 |
| 申请号 |
NZ20030539841 |
申请日期 |
2003.12.03 |
| 申请人 |
GLAXO GROUP LIMITED |
发明人 |
DEMONT, EMMANUEL H;FALLER, ANDREW;MACPHERSON, DAVID TIMOTHY;MILNER, PETER HENRY;NAYLOR, ALAN;REDSHAW, SALLY;STANWAY, STEVEN JAMES;VESEY, DAVID R;WALTER, DARYL S |
| 分类号 |
A61P25/28;C07D207/26;C07D207/267;C07D211/76;C07D275/02;C07D279/02;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D417/12;(IPC1-7):C07D207/26;A61K31/401;A61K31/45;A61K31/415;A61K31/541 |
主分类号 |
A61P25/28 |
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