Method of obtaining 9-deox-9a-aza-9a-methyl-9a-homoerythromycin A in non-crystalline form and method of obtaining 9-deox-9a-aza-9a-methyl-9a-homoerythromycin A in the form of crystalline dihydrate

摘要

The present invention describes new procedures for the preparation of the macrolide azithromycin in its non-crystalline and crystalline dihydrate forms, which are characterized and clearly differentiated by means of the following methods and techniques: 1. IR Spectroscopy. 2. Differential Scan Calorimetry (DSC). 3. X-Ray Diffraction. 4. Hygroscopicity. 5. Crystallinity test (Light Polarized Microscopy)