| 摘要 |
THE NOVEL N-(4-CARBAMIMIDOPHENYLAMINO) PHENYL-GLYCINEAMIDE DERIVATIVES OF THE FORMULA IN WHICH E, G1, G2, Q, R AND X1 TO X4 ARE EACH AS DEFINED IN THE DESCRIPTION, AND HYDRATES OR SOLVATES AND PHYSIOLOGICALLY ACCEPTABLE SALTS THEREOF CAN USED AS INHIBITORS OF THE FORMATION OF THE COAGULATION FACTORS XA, IXA AND THROMBIN INDUCED BY THE FACTOR VIIA AND BY THE TISSUE FACTOR, SPECIFICALLY AS MEDICAMENTS FOR THE TREATMENT AND/OR PREVENTION OF THROMBOSES, APOPLEXY, CARDIAC INFARCTION, INFLAMMATION AND ARTERIOSCLEROSIS OR AS ANTITUMOUR AGENTS. |
