发明名称 |
LOW-DOSE DOXEPIN FOR TREATMENT OF SLEEP DISORDERS IN ELDERLY PATIENTS |
摘要 |
Methods of treating sleep disorders, particularly certain aspects of insomnia, in elderly patients (65 years and older) by administering initial daily dosages of doxepin of 1-3 mg. These ultra-low initial dosages are more effective in elderly versus non-elderly patients in decreasing wake time during sleep, latency to persistent sleep and wake time after sleep, and are particularly efficacious in treating those conditions in the last hour of an 8-hour sleep cycle. Also, the dosages described herein are safe for elderly individuals. |
申请公布号 |
WO2007136845(A2) |
申请公布日期 |
2007.11.29 |
申请号 |
WO2007US12106 |
申请日期 |
2007.05.18 |
申请人 |
SOMAXON PHARMACEUTICALS, INC.;ROGOWSKI, ROBERTA L.;DUBE, SUSAN E.;JOCHELSON, PHILIP |
发明人 |
ROGOWSKI, ROBERTA L.;DUBE, SUSAN E.;JOCHELSON, PHILIP |
分类号 |
|
主分类号 |
|
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|