发明名称 |
METHOD OF AFFECTING SLEEP AND SLEEP-RELATED BEHAVIORS |
摘要 |
A method of affecting sleep and sleep-related behaviors of a mammal having a diurnal rhythm, by reducing the basal activity of the hypothalamus-pituitary-adrenal axis by administering an effective amount of a sensory regimen is disclosed. Such reduction may be accomplished by reducing at least one of the following: a. the average total daily amount of adrenocortical hormone; or b. the average total daily amount adrenocortical hormone minus the integrative measure of morning peak adrenocortical hormone. Preferably, such reduction also includes reducing at least one of the following: c. the level of adrenocortical hormone 4 hours to 8 hours after waking; d. the level of adrenocortical hormone in the period of time preceding bedtime; or e. the level of adrenocortical hormone below the onset of sleep threshold.
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申请公布号 |
US2007275102(A9) |
申请公布日期 |
2007.11.29 |
申请号 |
US20070623181 |
申请日期 |
2007.01.15 |
申请人 |
MCCULLOCH LAURA;WIEGAND BENJAMIN |
发明人 |
MCCULLOCH LAURA;WIEGAND BENJAMIN |
分类号 |
A61K31/56;A61K45/00;A61B5/00;A61K36/185;A61K38/22;A61M21/00;A61M21/02;A61P5/02;A61P25/20 |
主分类号 |
A61K31/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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