| 摘要 |
<p>There are presented compounds of the formula (I) wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP> and R<SUP>4</SUP> are as defined in the description and claims, or a pharmaceutically acceptable salt thereof, which are active adenosine A2B receptor antagonists and useful in the treatment of diabetes, diabetic retinopathy, asthma and diarrhea.</p> |
| 申请人 |
F. HOFFMANN-LA ROCHE AG;BRINKMAN, JOHN A.;CHEUNG, ADRIAN WAI-HING;FIROOZNIA, FARIBORZ;GUERTIN, KEVIN RICHARD;MARCOPULOS, NICHOLAS;QI, LIDA;RACHA, JAGDISH KUMAR;SARABU, RAMAKANTH;TAN, JENNY;TILLEY, JEFFERSON WRIGHT |
发明人 |
BRINKMAN, JOHN A.;CHEUNG, ADRIAN WAI-HING;FIROOZNIA, FARIBORZ;GUERTIN, KEVIN RICHARD;MARCOPULOS, NICHOLAS;QI, LIDA;RACHA, JAGDISH KUMAR;SARABU, RAMAKANTH;TAN, JENNY;TILLEY, JEFFERSON WRIGHT |
