| 发明名称 |
C-GLYCOLIPIDS WITH ENHANCED TH-1 PROFILE |
| 摘要 |
The invention is directed to novel synthetic C-glycolipids that selective ly induce a ThI -type immune response characterized by enhanced IL- 12 secre tion and increased activation of dendritic cells. The compounds of the inven tion are thereby useful in treating infections, cancers, cell proliferative disorders, and autoimmune diseases, both directly and as adjuvants. |
| 申请公布号 |
CA2653647(A1) |
申请公布日期 |
2007.11.29 |
| 申请号 |
CA20072653647 |
申请日期 |
2007.05.22 |
| 申请人 |
RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEWYORK;NEW YORK UNIVERSITY;THE AARON DIAMOND AIDS RESEARCH CENTER FOR THE CITY OF NEW YORK, INC. |
发明人 |
YANG, GUANGLI;TSUJI, MORIYA;FRANCK, RICHARD;CHEN, GUANGWU |
| 分类号 |
A61K31/70;C07H7/02 |
主分类号 |
A61K31/70 |
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