发明名称 INTRANASAL ADMINISTRATION OF KETAMINE TO TREAT DEPRESSION
摘要 Methods and compositions for the treatment of treatment-resistant depression are described. More specifically, the invention demonstrates that intranasal administration of ketamine is effective to ameliorate the symptoms of depression in a patient who has not responded to an adequate trial of one antidepressant in the current episode and has recurrent or chronic depressive symptoms (> 2 years).
申请公布号 WO2007111880(A9) 申请公布日期 2007.11.29
申请号 WO2007US06898 申请日期 2007.03.20
申请人 MOUNT SINAI SCHOOL OF MEDICINE;THE GOV. OF THE USA, AS REPRESENTED BY THE SECRETARY OF HEALTH & HUMAN SERVICES NATIONAL INSTITUTES;YALE UNIVERSITY SCHOOL OF MEDICINE;CHARNEY, DENNIS, S.;MATHEW, SANJAY, J.;MANJI, HUSSEINI, K.;ZARATE, CARLOS, A., JR.;KRYSTAL, JOHN, H. 发明人 CHARNEY, DENNIS, S.;MATHEW, SANJAY, J.;MANJI, HUSSEINI, K.;ZARATE, CARLOS, A., JR.;KRYSTAL, JOHN, H.
分类号 A61K31/137 主分类号 A61K31/137
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