NOVEL AMINOCALIXARENE DERIVATIVES, METHOD OF PREPARATION THEREOF, AND SELF-ASSEMBLED MONOLAYER PREPARED BY THE METHOD, FIXING METHOD OF OLIGO-DNA BY SPONTANEOUS AND IRREVERSIBLE MOLECULAR RECOGNITION OF OLIGO-DNA TO THE SELF-ASSEMBLED MONOLAYER, AND OLIGO-DNA CHIP PREPARED BY THE METHOD

摘要

An aminocalixarene derivative is provided to enable the irreversible molecular recognition of continuous guanine groups. An aminocalixarene derivative has a structure represented by the following formula 1, wherein R1, R2, R3, R4, R5, R6, R7, R8, R'1, R'2, R'3, R'4, R'5, R'6, R'7, and R'8 are, independently of one another, selected from the group consisting of -H, -CH3, -C2H5, -C3H7, -OCH3, -Cl, -C6H5, -OH, -OCH2CH3, -Br, -CF3, -OCH2C6H5, -OC6H5, -OC6H4CH3, -OC6H4C(CH3)3, -OC6H4CF3, -OC6H4Cl, -OCOCH3, -NHCOCH3, -CONHCH3, -CN, COOH, and -COOR(wherein, R represents -CH3 or -C2H5), with the proviso that all of R1, R2, R3, R4, R5, R6, R7, R8, R'1, R'2, R'3, R'4, R'5, R'6, R'7, and R'8 are not identical.