| 发明名称 |
THIAZOLO-PYRAMIDINE / PYRIDINE UREA DERIVATIVES AS ADENOSINEA2B RECEPTOR ANTAGONISTS |
| 摘要 |
There are presented compounds of the formula (I) wherein R1, R2, R3 and R 4 are as defined in the description and claims, or a pharmaceutically accept able salt thereof, which are active adenosine A2B receptor antagonists and u seful in the treatment of diabetes, diabetic retinopathy, asthma and diarrhe a.
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| 申请公布号 |
CA2651769(A1) |
申请公布日期 |
2007.11.29 |
| 申请号 |
CA20072651769 |
申请日期 |
2007.05.08 |
| 申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
MARCOPULOS, NICHOLAS;QI, LIDA;GUERTIN, KEVIN RICHARD;TILLEY, JEFFERSON WRIGHT;SARABU, RAMAKANTH;TAN, JENNY;RACHA, JAGDISH KUMAR;CHEUNG, ADRIAN WAI-HING;BRINKMAN, JOHN A.;FIROOZNIA, FARIBORZ |
| 分类号 |
C07D513/04;A61K31/437;A61K31/519;A61P3/10;C07D521/00 |
主分类号 |
C07D513/04 |
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