发明名称 Biomarker isolation and use thereof to characterize physiological state
摘要 The present invention relates to compositions and methods for characterizing the physiological state of a living system, including cells, tissues, organs, and whole organisms. The methods involve capturing biomarkers from the living system, and correlating their presence or absence to a physiological state. The biomarkers can be captured from the system, and then detected using any suitable analytical system to determine their presence or absence. In one embodiment, the invention relates to a method of detecting a polypeptide biomarker in a blood serum or plasma sample obtained from a single subject with an affinity ligand which is capable of binding to a plurality of different polypeptide biomarkers derived from the same parental molecule.
申请公布号 US2007275483(A1) 申请公布日期 2007.11.29
申请号 US20060639414 申请日期 2006.12.15
申请人 LIOTTA LANCE;PETRICOIN EMANUEL 发明人 LIOTTA LANCE;PETRICOIN EMANUEL
分类号 G01N33/53;C12Q1/68 主分类号 G01N33/53
代理机构 代理人
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