| 发明名称 |
Mptens as Modifiers of the Pten/Igf Pathway and Methods of Use |
| 摘要 |
Human MPTEN genes are identified as modulators of the PTEN/IGF pathway, and thus are therapeutic targets for disorders associated with defective PTEN/IGF function. Methods for identifying modulators of PTEN/IGF, comprising screening for agents that modulate the activity of MPTEN are provided.
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| 申请公布号 |
US2007274914(A1) |
申请公布日期 |
2007.11.29 |
| 申请号 |
US20040556630 |
申请日期 |
2004.05.13 |
| 申请人 |
EXELIXIS, INC. |
发明人 |
SONG CHUNYAN;OLLMANN MICHAEL M.;LICKTEIG KIM;ZHANG HAIGUANG;BJERKE LYNN M. |
| 分类号 |
A61K49/00;A61P5/00;C07K14/47;C12N;C12N5/00;C12N5/02;C12Q1/42;C12Q1/68;G01N33/50;G01N33/53;G01N33/566;G01N33/574;G01N33/74 |
主分类号 |
A61K49/00 |
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