发明名称 |
METHOD AND APPARATUS FOR LYMPH NODE MAPPING |
摘要 |
A system and method for optical lymph node mapping. The system is useful for guiding sentinel lymph node biopsy surgeries. A contrast agent that includes a fluorescent dye is injected near the site of a malignancy. The contrast agent drains into the lymphatic system, collecting in a sentinel node or nodes. The system utilizes one or more low-power continuous-wave lasers or light-emitting diodes modulated with a digital code sequence to probe the tissue suspected of containing the sentinel node. When the light is incident near the sentinel node, it will excite fluorescence from the dye. A portion of the scattered fluorescent light is captured with one or more photo-detectors. A correlation of the photo-detector signal and the digital code sequence is calculated to produce an estimate of the distribution of flight times for photons traveling from a given source to a given detector. The flight time distributions are used along with the measured amplitudes to reconstruct a map of contrast agent location within the tissue.
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申请公布号 |
US2007276257(A1) |
申请公布日期 |
2007.11.29 |
申请号 |
US20060381443 |
申请日期 |
2006.05.03 |
申请人 |
HEANUE JOHN F;HEANUE JOSEPH A;WILFLEY BRIAN P;LOWELL AUGUSTUS P |
发明人 |
HEANUE JOHN F.;HEANUE JOSEPH A.;WILFLEY BRIAN P.;LOWELL AUGUSTUS P. |
分类号 |
A61B6/00 |
主分类号 |
A61B6/00 |
代理机构 |
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主权项 |
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地址 |
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