VERFAHREN ZU HERSTELLUNG VON AKTIVIERTEN POLYETHYLENGLYKOLEN

摘要

The present invention relates to a process for the preparation of activated polyethylene glycols, or PEG(NPC)²s, comprising reacting polyethylene glycol with an activator while in the presence of an aromatic nitrogen containing heterocyclic base. The process is carried out at temperatures ranging from about 20 to about 30° C., more preferably at room temperature, and under stoichiometric conditions.