发明名称 |
COMPOSITION FOR DIAGNOSIS OF AMYLOID-RELATED DISEASE |
摘要 |
It is intended to provide a composition which contains a compound represe nted by the following general formula (I): wherein R1 represents 5-iodothiop hen-2-yl, etc.; and R2 represents 4-dimethylaminophenyl, etc. Because of hav ing a high specificity of binding to amyloid .beta.-protein, a high blood-br ain-barrier permeability and an ability to quickly disappear from parts othe r than a senile plaque in the brain, the above compound is useful in diagnos ing an amyloid-related disease such as Alzheimer's disease.
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申请公布号 |
CA2652440(A1) |
申请公布日期 |
2007.11.29 |
申请号 |
CA20072652440 |
申请日期 |
2007.05.22 |
申请人 |
NAGASAKI UNIVERSITY |
发明人 |
ONO, MASAHIRO;HARATAKE, MAMORU;MORI, HIROSHI;NAKAYAMA, MORIO |
分类号 |
A61K51/00;C07D213/61;C07D233/64;C07D277/24;C07D307/42;C07D333/28;C07D333/36;C07D409/06 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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