发明名称 COMPOSITION FOR DIAGNOSIS OF AMYLOID-RELATED DISEASE
摘要 It is intended to provide a composition which contains a compound represe nted by the following general formula (I): wherein R1 represents 5-iodothiop hen-2-yl, etc.; and R2 represents 4-dimethylaminophenyl, etc. Because of hav ing a high specificity of binding to amyloid .beta.-protein, a high blood-br ain-barrier permeability and an ability to quickly disappear from parts othe r than a senile plaque in the brain, the above compound is useful in diagnos ing an amyloid-related disease such as Alzheimer's disease.
申请公布号 CA2652440(A1) 申请公布日期 2007.11.29
申请号 CA20072652440 申请日期 2007.05.22
申请人 NAGASAKI UNIVERSITY 发明人 ONO, MASAHIRO;HARATAKE, MAMORU;MORI, HIROSHI;NAKAYAMA, MORIO
分类号 A61K51/00;C07D213/61;C07D233/64;C07D277/24;C07D307/42;C07D333/28;C07D333/36;C07D409/06 主分类号 A61K51/00
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