发明名称 IMPURITIES OF DONEPEZIL
摘要 The present invention relates to impurities of donepezil, or a pharmaceut ically acceptable salt thereof, which may be produced during synthesis and s torage of donepezil, or a pharmaceutically-acceptable salt thereof, and to m ethods of identifying such impurities.The invention also relates to the use of these impurities in analytical techniques and to product that contain cer tain low levels of these impurities in particular the following impurities a re disclosed: formula (I) and formula (II).
申请公布号 CA2653538(A1) 申请公布日期 2007.11.29
申请号 CA20072653538 申请日期 2007.05.18
申请人 PLIVA HRVATSKA D.O.O. 发明人 GREBENAR, IVICA;SAMARDZIC, ZRINKA MASTELIC;KORUZNJAK, JASNA, DOGAN;LERMAN, LIDIJA;ZIOBRO, BARBARA;MANIKOWSKI, ANDRZEJ;KACZOROWSKA, KATARZYNA;KRIZMANIC, IRENA
分类号 C07D211/32;A61K31/445;C07C225/18;G01N30/02;G01N30/90;G01N33/15 主分类号 C07D211/32
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