DIAGNOSTIC AND THERAPEUTIC USES OF PEPTIDES FOR PRE-FORMS OF TYPE 2 DIABETES AND CONDITIONS ASSOCIATED THEREWITH

摘要

The present invention is in the field of diagnostics and therapeutics. Specifically, the present invention provides methods for diagnosis and therapy of diseases and conditions associated with oxidative stress such as Type 2 diabetes, hyperglycaemia, pre-eclampsia, aging, etc. Furthermore the invention provides peptides, binding agents recognizing said peptides, diagnostic assay kits, and compositions suitable for medical purposes. The peptides of the invention are characterized by a C-terminal, non-enzymatic originated amide or by a nitric oxide binding site. The peptides of the invention are suitable as biomarker or as therapeutic substances capable to function as nitric oxide delivery vehicles.