发明名称 |
IMMUNO-RNA-CONSTRUCTS |
摘要 |
<p>Subject of the invention is a compound, consisting of a targeting moiety which specifically binds to a disease related cell surface marker, a nucleic acid which specifically induces cell death and a linker, wherein the linker covalently links the targeting moiety to the nucleic acid. Subject of the invention are also medicaments comprising the compound and their use as a medicament for the treatment of diseases, including proliferative diseases.</p> |
申请公布号 |
WO2007071777(A3) |
申请公布日期 |
2007.11.22 |
申请号 |
WO2006EP70116 |
申请日期 |
2006.12.21 |
申请人 |
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;BARTH, STEFAN;WUELLNER, ULRICH;NEEF, INGA |
发明人 |
BARTH, STEFAN;WUELLNER, ULRICH;NEEF, INGA |
分类号 |
A61K47/48;A61P35/00;A61P37/00;C12N15/11;C12N15/113;C12N15/115 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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