ASSESSMENT OF SLEEP QUALITY AND BREATHING BASED ON CARDIOPULMONARY COUPLING

摘要

An assessment of sleep quality breathing is determined from the cardiopulmonary coupling between two physiological data series. An R-R interval series is derived from an electrocardiogram (ECG) signal (203). The normal beats from the R-R interval series are extracted to produce a normal-to- normal (NN) interval series (206). The amplitude variations in the QRS complex are used to extract to a surrogate respiration signal (i.e., ECG-derived respiration (EDR)) that is associated with the NN interval series (209). The two series are corrected to remove outliers, and resampled (212). The cross-spectral power and coherence of the two resampled signals are calculated over a plurality of coherence windows (218). For each coherence window, the product of the coherence and cross- spectral power is used to calculate coherent cross power (221 ). Using the appropriate thresholds for the coherent cross power, the proportion of sleep spent in CAP, non-CAP, and wake and/or REM are determined (224).