发明名称 NOVEL SALT FORMS OF (2S)-(4E)-N-METHYL-5-[3-(5-ISOPROPOXYPYRIDIN)YL]-4-PENTEN-2-AMINE
摘要 Phosphoric acid, edisylic acid (1,2-ethanedisulfonic acid), citric acid, orotic acid (uracil-6-carboxylic acid), R-mandelic acid, sulfuric acid, 1,5-naphthalenedisulfonic acid, D-aspartic acid, and lysine monohydrochloride salts of (2S)-(4E)-N-methyl-5-[3-(5-isopropoxypyridin)yl]-4-penten-2-amine, and methods for their preparation, pharmaceutical compositions comprising said salts, and use, are disclosed. The salts can be administered to patients susceptible to or suffering from conditions and disorders, such as central nervous system disorders, to treat and/or prevent such disorders.
申请公布号 WO2007134038(A2) 申请公布日期 2007.11.22
申请号 WO2007US68452 申请日期 2007.05.08
申请人 ASTRAZENECA AB;TARGACEPT, INC.;BOHLIN, MARTIN, HANS;DULL, GARY, M.;ERIKSSON, CAROLINE;MILLER, CRAIG, H.;MUNOZ, JULIO, A.;SEBHATU, TESFAI 发明人 BOHLIN, MARTIN, HANS;DULL, GARY, M.;ERIKSSON, CAROLINE;MILLER, CRAIG, H.;MUNOZ, JULIO, A.;SEBHATU, TESFAI
分类号 C07D213/38 主分类号 C07D213/38
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