发明名称 |
USE OF CHLOROQUINE TO TREAT METABOLIC SYNDROME |
摘要 |
The present invention provides methods and compositions for modulating certain metabolic processes and for treating a variety of disorders associated with metabolic syndrome, including insulin related disorders, ischemia, oxidative stress, atherosclerosis, hypertension, obesity, abnormal lipid metabolism, and stroke by administering an effective dose of a chloroquine compound. The invention also provides methods and compositions relating to administering an effective dose of a chloroquine compound in combination with at least a second pharmaceutically active ingredient or compound including an antihyperglycemic diabetes treatment, an antihypertensive agent, an antithrombotic agent, and /or an inhibitor of cholesterol synthesis or absorption.
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申请公布号 |
WO2007059372(A3) |
申请公布日期 |
2007.11.22 |
申请号 |
WO2006US60391 |
申请日期 |
2006.10.31 |
申请人 |
ST. JUDE CHILDREN'S RESEARCH HOSPITAL;THE WASHINGTON UNIVERSITY;KASTAN, MICHAEL, B.;SEMENKOVICH, CLAY, F.;SCHNEIDER, JOCHEN |
发明人 |
KASTAN, MICHAEL, B.;SEMENKOVICH, CLAY, F.;SCHNEIDER, JOCHEN |
分类号 |
A61K31/435;A61K31/03 |
主分类号 |
A61K31/435 |
代理机构 |
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