| 发明名称 |
Nadks as Modifiers of Branching Morphogenesis and Methods of Use |
| 摘要 |
Human NADK genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morpho-genesis, comprising screening for agents that modulate the activity of NADK are provided.
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| 申请公布号 |
US2007269378(A1) |
申请公布日期 |
2007.11.22 |
| 申请号 |
US20040556440 |
申请日期 |
2004.06.18 |
| 申请人 |
EXELIXIS INC. |
发明人 |
PLOWMAN GREGORY D.;KARIM FELIX D.;SWIMMER CANDACE;HABECK HINRICH A.;KOBLIZEK THOMAS I.;SCHULTE-MERKER STEFAN;EISENMANN ULRIKE;STOTT GORDON M.;TROWE TORSTEN;VOGEL ANDREAS M.;ODENTHAL JOERG H.;SCHEEL JOCHEN K.;WILL TORSTEN T.;JIN YINSHENG;BJERKE LYNN M.;HEUER TIMOTHY S. |
| 分类号 |
A61K49/00;A61P43/00;C12N5/06;C12Q1/48;C12Q1/68 |
主分类号 |
A61K49/00 |
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