| 摘要 |
A device and method for closure of a body channel of a patient, such as a patent foramen ovale. The device includes a frame member having a collapsed condition and an expanded condition. The frame member is sized and arranged to be percutaneously insertable into an area of the foramen ovale when in the collapsed condition, and to substantially span the foramen ovale when in the expanded condition. A promoter carried by the frame member, such as a clot-promoting composition and/or a tissue growth-promoting composition, is capable of promoting biological formation with the tissue bordering the foramen ovale to effect a closure of the foramen ovale.
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