摘要 |
The present invention provides for a novel process of making 6-carboxylic acid derivatives of pyrido[2,3-<d]pyrimidin-7-one's, as well as a novel process for making 8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-{[2-hydroxy-l- (hydroxymethyl)ethyl]-amino}pyrido[2,3-d]pyrimidin-7(8H)-one, and salts thereof. |
申请人 |
GLAXO GROUP LIMITED;APPLEBY, JOHN ROBERT, GEORGE;HUMPHRIES, LESLEY, ANNE;BLATCHER, PHILIP;ABU KHALIL, AS'AD;KASPAREC, JIRI;DIEDERICH, ANN, M.;VERNON, LOIS, E.;TAGGART, JOHN, J.;LLOYD, RICHARD, S.;SPOORS, PAUL, G. |
发明人 |
APPLEBY, JOHN ROBERT, GEORGE;HUMPHRIES, LESLEY, ANNE;BLATCHER, PHILIP;ABU KHALIL, AS'AD;KASPAREC, JIRI;DIEDERICH, ANN, M.;VERNON, LOIS, E.;TAGGART, JOHN, J.;LLOYD, RICHARD, S.;SPOORS, PAUL, G. |