发明名称 |
Combinations of HMG CoA reductase inhibitors and negatively charged phospholipids and uses thereof |
摘要 |
The present invention provides combinations of pharmaceutically active agents (i.e. statins and negatively charged phospholipids) for treating or preventing atherosclerosis or coronary artery disease (CAD) in mammals, and methods therefore. In particular, these combinations and methods find utility for achieving one or more of the following effects in a subject: (1) a reduction in plasma levels of low-density lipoprotein (LDL) cholesterol and very-low-density lipoprotein (VLDL) cholesterol; (2) an increase in plasma levels of high-density lipoprotein (HDL) cholesterol; and (3) a reduction in plasma levels of triglycerides.
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申请公布号 |
US2007269503(A1) |
申请公布日期 |
2007.11.22 |
申请号 |
US20060434157 |
申请日期 |
2006.05.16 |
申请人 |
BURGESS JAMES WALTER;SPARKS DANIEL |
发明人 |
BURGESS JAMES WALTER;SPARKS DANIEL |
分类号 |
A61K31/401;A61K9/127;A61K31/22;A61K31/366 |
主分类号 |
A61K31/401 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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