VANCOMYCIN FORMULATIONS HAVING REDUCED AMOUNT OF HISTAMINE
摘要
A time-released formulation of vancomycin. The invention also includes a vancomycin composition having a reduced level of histamine and a process for reducing the level of histamine in a vancomycin composition. The invention also includes a pharmaceutical composition containing vancomycin that reduces the incidence of Red Man Syndrome, phlebitis, and hypotension. The invention further includes a histamine-free growth media that supports growth of Amycolatopsis orientalis and the fermentation of vancomycin.
申请公布号
WO2007053558(A3)
申请公布日期
2007.11.22
申请号
WO2006US42339
申请日期
2006.10.31
申请人
HOSPIRA, INC.;MAY, THOMAS, B.;BLESSING, RICHARD;MENON, SUKUMARAN, K.;OSTROW, DAVID, H.
发明人
MAY, THOMAS, B.;BLESSING, RICHARD;MENON, SUKUMARAN, K.;OSTROW, DAVID, H.