APPARATUS AND METHOD FOR COUPLING MICROFLUIDIC SYSTEMS WITH A MASS SPECTROMETER UTILIZING RAPID VOLTAGE SWITCHING

摘要

The invention relates to an apparatus for coupling microfluidic systems with electrospray ionization mass spectrometry utilizing a hydrodynamic flow. The invention also relates to a method of preventing a sample in a main channel (25) of a microfluidic device (11) from migrating down either a first side channel (31) or a second side channel (33) by rapidly alternating a voltage being applied to the first side channel (31) and the second side channel (33).