LINKER MOLECULES FOR SUBSTRATE SURFACE TREATMENT AND SPECIFIC PROTEIN IMMOBILIZATION, AND METHOD FOR PREPARING THE SAME

摘要

The present invention relates to a linker molecule for immobilizing a protein on a substrate surface and a preparation method thereof. More specifically, relates to a linker molecule, which has a functional group binding to a substrate, and a functional group binding to a protein, at both ends of a protein-immobilizing ligand, respectively, as well as a preparation method thereof and a method for immobilizing a protein through the linker molecule. The disclosed linker molecule can form a self-assembled monolayer on a substrate selected from the group consisting of gold, silver, semiconductor, glass, silicon and polymer, so as to minimize non-specific binding in a process of immobilizing a protein on the substrate. Accordingly, the linker molecule will be useful for biochips, biosensors and other supports for protein immobilization.