Azasugar derivatives, heparanase inhibitors, method for preparing same, compositions containing same, use thereof

摘要

The invention concerns heparanase inhibiting compounds of general formula (I) wherein R represents a hydrogen atom, an hydroxyl radical, a -OSO₃^- radical, a -O-(C₁-C₅)alkyl radical or an -O- aralkyl radical; Z represents a COO^- radical or a hydroxyl radical; X represents -OH or a saccharide unit of formula A, Y represents H, C₁-C₅ alkyl or a saccharide unit of formula D; in free form or in the form of pharmaceutically acceptable salts formed with a base or an acid as well as in the form of solvates or hydrates. The derivatives of the invention are useful as medicines.