发明名称 SUBSTITUTED BETA-PHENYL-ALPHA-HYDROXY PROPANOIC ACID, SYNTHESIS METHOD AND USE THEREOF
摘要 Compounds represented by general formula (I), in which R1, R2, R3 each ot her independently selected from H, OH, F, Cl, Br, methoxy and ethoxy; altera tive R1and R2 forms ~OCH2O- together,R3 selected from H, OH, methoxy, ethoxy and halo; R4 selected from OH or acyloxy; R5 selected from cycloalkoxy, ami no, and substituted amino, and when R5 represents amino, R1, R2, R3 don't re present H at same time. A process for preparing compounds represented by gen eral formula (I) and usage thereof for preventing and treating cardiovascula r and cerebrovascular diseases.
申请公布号 CA2652299(A1) 申请公布日期 2007.11.22
申请号 CA20072652299 申请日期 2007.05.14
申请人 NORTHWEST UNIVERSITY 发明人 ZHENG, XIAOHUI;ZHANG, QUNZHENG;WANG, SHIXIANG;ZHAO, XINFENG
分类号 C07C69/732;A61K31/216;A61K31/36;A61K31/443;A61P9/00;C07C69/653;C07C233/48;C07D317/54;C07D317/58;C07D407/12 主分类号 C07C69/732
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