METHOD OF DIAGNOSIS OF TOXICITY AND EXPOSURE FOR DEOXYNIVALENOL USING HAPTOGLOBIN-SPECIFIC PROTEIN AND THE DIAGNOSTIC KIT
摘要
A method and kit for diagnosis of toxicity and exposure for deoxynivalenol are provided to improve detection convenience and time of deoxynivalenol by detecting increase of a haptoglobin level in blood plasma. A method for diagnosis of toxicity and exposure for deoxynivalenol comprises the steps of: coating an ELISA(enzyme-linked immunosorbent assay) plate with an anti-haptoglobin antibody; adding diluted blood plasma into the plate and reacting them for a certain period; reacting the plate with a secondary antibody to determine presence of haptoglobin having the amino acid sequence of SEQ ID NO:1. A kit for diagnosis of toxicity and exposure for deoxynivalenol comprises an antibody specific to haptoglobin or its immunogenic fragment, fixed in a reaction region of a strip.
申请公布号
KR20070111231(A)
申请公布日期
2007.11.21
申请号
KR20060044347
申请日期
2006.05.17
申请人
REPUBLIC OF KOREA(MANAGEMENT : MINISTRY OF AGRICULTURE AND FORESTRY, NATIONAL VETERINARY RESEARCH--)
发明人
CHO, JOON HYOUNG;JEONG, SANG HEE;KU, HYUN OK;PYO, HYUN MI;KIM, EUN JOO;ROH, IN SOON;KIM, MIN JEONG;JEAN, YOUNG HWA;LEE, O SOO