发明名称 |
METHOD FOR MORPHOMETRIC CLASSIFICATION OF NUCLEOLI IN CASE OF PRE-TUMOR AND TUMOR GYNECOLOGICAL DISEASES |
摘要 |
FIELD: medicine, histology, pathohistology, oncology. ^ SUBSTANCE: it is necessary to conduct computed morphometry of nucleoli stained with 50%-silver nitrate solution The values of nucleoli' areas being within 25-75%% quartiles should be analyzed. Metric parameters of nucleoli areas should be transformed into conditional units of areas - average values of the interval of area referred to the average value of the least interval for normal epithelium which was conditionally considered to correspond to diploid set of DNA nucleus. Based upon frequency characteristics of each interval transformed into conditional units of area it is necessary to obtain histograms to observe qualitative peculiarity in distributing the areas of nucleoli for each clinico-morphological form. The innovation enables to elaborate morphometric classification of the nucleoli associated with nuclear ploidy. ^ EFFECT: higher efficiency of classification. ^ 2 ex, 2 tbl |
申请公布号 |
RU2310394(C1) |
申请公布日期 |
2007.11.20 |
申请号 |
RU20060117133 |
申请日期 |
2006.05.18 |
申请人 |
GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA DAL'NEVOSTOCHNYJ GOSUDARSTVENNYJ MEDITSINSKIJ UNIVERSITET FEDERAL'NOGO AGENTSTVA PO ZDRAVOOKHRANENIJU I SOTSIAL'NOMU RAZVITIJU |
发明人 |
TSYGANKOV VASILIJ IVANOVICH;IEVLEVA NADEZHDA FEDOROVNA |
分类号 |
A61B10/00;G01N1/30;G01N15/02 |
主分类号 |
A61B10/00 |
代理机构 |
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