发明名称 OSTEOGENIC GROWTH OLIGOPEPTIDES AS SIMULATORS OF HEMOPOIESIS
摘要 FIELD: medicine, peptides. ^ SUBSTANCE: invention relates to osteogenic growth oligopeptides used as stimulators of hemopoiesis. Invention proposes using an oligopeptide of molecular mass in the range from 200 to 1000 Da, comprising one of the following sequence: Tyr-Gly-Phe-Gly-Gly, Met-Tyr-Gly-Phe-Gly-Gly used in preparing a pharmaceutical composition and enhancing mobilization of hemopoietic stem cells from many differentiation line into peripheral blood, in particular, CD34-positive hemopoietic stem cells. Advantage of the invention involves expanding field in using oligopeptides used in stimulation of hemopoiesis. ^ EFFECT: enhanced and valuable properties of oligopeptides. ^ 34 cl, 2 tbl, 7 dwg, 4 ex
申请公布号 RU2310468(C2) 申请公布日期 2007.11.20
申请号 RU20040105258 申请日期 2001.07.29
申请人 JISUM RESECH DEVELOPMENT KOMPANI OF DZE KHIBROU JUNIVESITI OF IERUSALIM 发明人 BAB ITAJ;KHOREV MIKHAIL;SHTEIR AR'E;MUKHLRAD ANDRASH;MANSUR NURA;GUREVICH OL'GA;GRINBERG TSVI;ROSINI SERDZHIO;TRASTSIATI SIL'VIA;PETRINI MARIO
分类号 A61K38/07;A61K38/08;A61P7/00;A61P35/02;C07K7/00;C12N5/00;C12N5/071;C12N5/0789 主分类号 A61K38/07
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