摘要 |
<p>The invention relates to methods for the prevention and/or treatment of tinnitus in-duced by cochlear excitotoxicity. In these methods, a pharmaceutical composition com-prising an NMDA receptor antagonist is administered to an individual in need of such treatment by appropriate devices and/or formulations for local administration to the inner ear. The tinnitus to be prevented and/or treated may be provoked by acoustic trauma, presbycusis, ischemia, anoxia, treatment with one or more ototoxic medications, sudden deafness, or other cochlear excitotoxic-inducing occurrence.</p> |