发明名称 |
Process for preparing N6-substituted aminopurine ribofuranose necleosides |
摘要 |
An improved process for preparing N6 -substituted aminopurine ribofuranose nucleosides. Compounds of this type are known to be usefull in the prepartation of compounds having activitity at adenosine receptors, e.g. Adenosine A1 receptor. The process comprises the step of reacting a 6-halopurine ribofuranose nucleoside with an amine in the presence of CaCO3 , wherein acid is added to the reaction mixture.
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申请公布号 |
US7297787(B2) |
申请公布日期 |
2007.11.20 |
申请号 |
US20030471682 |
申请日期 |
2003.09.12 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
BERRY MALCOLM;ROBERTS JOHN C.;XIE SHIPING |
分类号 |
C07H19/167;A61K31/7076;A61P43/00;C07H1/00;C07H19/16 |
主分类号 |
C07H19/167 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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