| 发明名称 |
Inhibitors of cathepsin S |
| 摘要 |
The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
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| 申请公布号 |
US7297714(B2) |
申请公布日期 |
2007.11.20 |
| 申请号 |
US20040970344 |
申请日期 |
2004.10.20 |
| 申请人 |
IRM LLC |
发明人 |
LIU HONG;ALPER PHILLIP;MUTNICK DANIEL;KARANEWSKY DONALD |
| 分类号 |
A61K31/4025;A61K;A61K31/34;A61K31/341;A61K31/35;A61K31/365;A61K31/452;A61K31/496;A61K31/5375;A61K31/5377;A61K31/541;C07D307/04;C07D307/32;C07D307/33;C07D405/12;C07D407/12;C07D413/02;C07D413/06;C07D413/12;C07D417/02 |
主分类号 |
A61K31/4025 |
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