发明名称 METHOD FOR PREPARING HYDROPHILIC COMPLEX BASED ON FLAVONOLIGNANS AND PHOSPHOLIPIDS
摘要 FIELD: medicine, pharmacology. ^ SUBSTANCE: method involves interaction of flavonolignans and phospholipids in organic medium followed by drying the prepared mixture by lyophilization or spraying drying. Preliminary an aqueous dispersion of phospholipids is prepared in the concentration 0.5-10 weight% containing an acceptable saccharide in the concentration 2-10 weight%. Then a mixture of flavolignans and phospholipids taken in the ratio from 10:0.1 to 10:1 in suitable organic solvent is injected to the prepared dispersion. Invention provides enhancing bioavailability of product. ^ EFFECT: improved preparing method. ^ 3 cl, 2 tbl, 4 ex
申请公布号 RU2310453(C1) 申请公布日期 2007.11.20
申请号 RU20060105854 申请日期 2006.02.28
申请人 AVTONOMNAJA NEKOMMERCHESKAJA ORGANIZATSIJA NAUCHNO-TEKHNICHESKIJ TSENTR "FARMBIOPRESS" 发明人 LUTSENKO ELENA VALER'EVNA;LUTSENKO SERGEJ VIKTOROVICH;FEL'DMAN NATAL'JA BORISOVNA
分类号 A61K31/685;A61K31/352 主分类号 A61K31/685
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