ПРОИЗВОДНЫЕ 1, 1, 1-ТРИФТОР-4-ФЕНИЛ-4-МЕТИЛ-2-(1H-ПИРРОЛО 2, 3-С ПИРИДИН-2-ИЛМЕТИЛ)ПЕНТАН-2-ОЛА И РОДСТВЕННЫЕ СОЕДИНЕНИЯ, КАК ГЛЮКОКОРТИКОИДНЫЕ ЛИГАНДЫ ДЛЯ ЛЕЧЕНИЯ ВОСПАЛИТЕЛЬНЫХ ЗАБОЛЕВАНИЙ И ДИАБЕТА

摘要

Compounds of Formula (IA), (IB), (IC), and (ID) wherein R1, R2, R3, R4, R5, and R6 are as respectively defined herein for Formula (IA), (IB), (IC), and (ID), or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.