| 发明名称 |
1H-QUINAZ0LINE-2,4-DIONES AND THEIR USE AS AMPA-RECEPTOR LIGANDS. |
| 摘要 |
<p>The present invention relates to l H-Quinazoline-2,4-diones of formula (I) wherein R<sup>1</sup> and R<sup>2</sup> are as defined in the specification, their preparation, their use as AMPA-receptor ligands, in particular for the treatment of epilepsy or schizophrenia, and pharmaceutical compositions containing them. Further, intermediates for the manufacture of compounds of formula (I) and combinations comprising compounds of formula (I) are disclosed.</p> |
| 申请公布号 |
MX2007012592(A) |
申请公布日期 |
2007.11.16 |
| 申请号 |
MX20070012592 |
申请日期 |
2006.04.10 |
| 申请人 |
NOVARTIS AG. |
发明人 |
JOHANNE RENAUD;YVES AUBERSON;WOLFGANG FROESTL;MANUEL KOLLER;JOACHIM NOZULAK;HANS ALLGEIER;HENRI MATTES;DAVID ORAIN;PHILIPP FLOERSHEIM;DAVID CARCACHE;CHRISTEL GUIBOURDENCHE;JORG KALLEN |
| 分类号 |
C07D239/96;A61K31/517;A61P25/08;A61P25/18;C07C229/56;C07C229/64;C07C229/66;C07C255/18;C07C265/12;C07D207/32;C07D207/337;C07D231/12;C07D237/08;C07D239/26;C07D241/12;C07D249/06;C07D263/32;C07D307/16;C07D307/54;C07D309/12;C07D401/04;C07D403/04;C07D405/04;C07D413/04 |
主分类号 |
C07D239/96 |
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