METHOD FOR TREATMENT OF CONSTIPATION-PREDOMINANT IRRITABLE BOWEL SYNDROME
摘要
The present invention provides methods for treating constipation-predominant irritable bowel syndrome comprising administering to a patient in need thereof, a polymeric proanthocyanidin composition from a Croton species or Calophyllum species in an amount sufficient to treat constipation-predominant irritable bowel syndrome (c-IBS). Treatment of c-IBS includes the treatment of the constipation component of c-IBS as well as the pain and abdominal discomfort associated with c-IBS. In one embodiment, the polymeric proanthocyanidin compound is crofelemer. The present invention in an alternative embodiment also provides methods for treating alternating constipation-predominant/diarrhea-predominant irritable bowel syndrome.
申请公布号
WO2007130892(A2)
申请公布日期
2007.11.15
申请号
WO2007US67739
申请日期
2007.04.30
申请人
NAPO PHARMACEUTICALS, INC.;TRINE PHARMACEUTICALS, INC.;QUART, BARRY;ROSENBAUM, DAVID