发明名称 EFFICIENT PRODUCTION METHOD OF GENE RECOMBINATION WHOLE ANTIGEN USING INTERNAL RIBOSOME BINDING SITE
摘要 <P>PROBLEM TO BE SOLVED: To increase production of immunoglobulin molecules in immunoglobulin production using animal culture cells, by well balanced production of two kinds of polypeptide, i.e., heavy chain and light chain of immunoglobulin molecules. <P>SOLUTION: A recombinant vector is provided by being arranged, in downstream of a promotor, a base sequence (A) encoding the heavy chain composing the immunoglobulin molecule and a base sequence (B) encoding the light chain composing the immunoglobulin molecule, and, between the base sequence (A) and the base sequence (B), an internal ribosome binding sequence derived from mRNA encoding homeodomain protein Gtx. <P>COPYRIGHT: (C)2008,JPO&INPIT
申请公布号 JP2007295846(A) 申请公布日期 2007.11.15
申请号 JP20060126673 申请日期 2006.04.28
申请人 KANEKA CORP;JAPAN SCIENCE & TECHNOLOGY AGENCY;UNIV NAGOYA 发明人 IIJIMA SHINJI;KAMIHIRA MASAMICHI;NISHIJIMA KENICHI;KYOGOKU KENJI
分类号 C12N15/09;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/02;C12P21/08 主分类号 C12N15/09
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